This study may contribute to the search for novel radioprotective agents.Ĭos P, Calomme M, Sindambiwe J B, De Bruyne T, Cimanga K, Pieters L. austriaca possesses strong antioxidant properties, significantly reducing lipid peroxidation and the incidence of micronuclei (for 30.88 % and 35.56 %, respectively) while enhancing apoptosis with no perturbation of the cell cycle. Both extracts slowed down cell proliferation gradually, enabling more time for repair.
monogyna were observed, seen as a reduced incidence of radiation-induced micronuclei (19.23 % and 13.24 %, respectively), reduced levels of lipid peroxidation products (50.04 % and 13.18 %, respectively) and two-fold enhanced apoptosis. Significant radiorecovery potentials of C. Treatment with the lowest dose gave the best protective effect. Cell cultures were treated with four different doses of plant extracts (0.1 mg/mL to 0.4 mg/mL). austriaca aerial parts were γ-pyrones and secoiridoids. monogyna fruit was rich in procyanidins and flavonoids. mas leaves, ellagic and gallic acid were found to be the dominant compounds, whereas C. Maljen in Serbia, air-dried and powdered, and the total phenolic content was analyzed. Kern.) Holub (Gentianaceae) aerial parts on cultured human peripheral blood lymphocytes in vitro after irradiation with 2 Gy of 60Co γ-rays. (Cornaceae) leaves and Gentianella austriaca (A. The objective of the present study is to evaluate the radioprotective properties of extracts of Crataegus monogyna Jacq.
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